今年度、生命化学科で行われた研究の成果として下記の学術論文が発表されました（1月31日現在）。いずれも生命化学科の学生、大学院生、ポスドク、教員が中心になって行われた研究成果で、世界的に評価されている学術雑誌に論文が掲載されました。今後も生命化学科発の研究成果を発信して参ります。

2020年度に生命化学科の学生、大学院生、ポスドク、教員が中心になって作成し、受理された原著論文

1. Osamu Ohno, Takuro Terasaki, Takuya Sano, Yuki Hitomi, Junichiro Miyamoto, Kenji Matsuno. Inhibitory effects of biseokeaniamide A against lipopolysaccharide-induced signal transduction. Bioorganic & Medicinal Chemistry Letters, 30, 127069, 2020.
https://www.sciencedirect.com/science/article/abs/pii/S0960894X20301475

2. Miyako Naganuma, Hidetomo Yokoo, Takashi Misawa, Kenji Matsuno, Genichiro Tsuji, and Yosuke Demizu. Design and synthesis of 4-(2-pyrrolyl)-4-phenylheptane derivatives as estrogen receptor antagonists. Heterocycles, 101, 429-434, 2020.
https://www.heterocycles.jp/newlibrary/libraries/journal/101/2/current

3. Nobuhiro Aburai, Shun Tamura, Katsuya Abe. Enhancement of carotenogenesis regulated by phosphorylation signaling in the aerial microalga Coelastrella sp. KGU-Y002. Phytochemistry Letters, 40. 121-125.
https://www.sciencedirect.com/science/article/abs/pii/S1874390020306790

4. Nobuhiro Aburai, Junko Oe, Katsuya Abe. Heterotrophic Microalgae Cultivation Using Jellyfish Protein Extract to Produce Bioactive Peptides. Waste and Biomass Valorization, 2020.
https://doi.org/10.1007/s12649-020-01261-5

5. Nobuhiro Aburai, Ryota Kunishima, Fusako Iijima, Katsuhiko Fujii. Effects of light-emitting diodes (LEDs) on lipid production of the aerial microalga Coccomyxa sp. KGU-D001 under liquid- and aerial-phase conditions. Journal of Biotechnology, 323, 274-282, 2020.
https://www.sciencedirect.com/science/article/abs/pii/S0168165620302418

6. Masahiro Kimura, Takashi Watanabe, Kazutaka Sekine, Hitomi Ishizuka, Aoi Ikejiri, Masayoshi Sakaguchi, Minori Kamaya, Daisuke Yamanaka, Vaclav Matoska, Peter O. Bauer, Fumitaka Oyama. Comparative functional analysis between human and mouse chitotriosidase: Substitution at amino acid 218 modulates the chitinolytic and transglycosylation activity. International Journal of Biological Macromolecules, 164, 2895-2902, 2020.
https://www.sciencedirect.com/science/article/pii/S0141813020342653

7. Kenshi Togashi, Satoshi Suzuki, Sae Morita, Yuki Ogasawara, Yasutada Imamura, Yongchol Shin. Excessively activated plasminogen in human plasma cleaves VWF multimers and reduces collagen-binding activity. The Journal of Biochemistry, 168, 355–363, 2020.
https://academic.oup.com/jb/article-abstract/168/4/355/5826353?redirectedFrom=fulltext

8. Osamu Ohno, Keigo Sato, Ryo Honma, Ruri Chiba, Kenji Matsuno. Anti-apoptotic activity of methyl (3R,4E,6Z,15E)-3-hydroxyoctadecatrienoate in human cervical carcinoma HeLa cells. Bioscience, Biotechnology, and Biochemistry, 2021 in press
https://academic.oup.com/bbb/advance-article/doi/10.1093/bbb/zbaa006/6104863

9. Miyuki Kumazawa, Manabu Tejima, Miwa Fukuda, Shota Takeda, Kenji Suzuki, Yukiko Mizumoto, Kakeru Sato, Minoru Waki, Hiroyuki Miyachi, Akira Asai, Osamu Takikawa, Tomoko Hashimoto, Osamu Ohno, Kenji Matsuno. Discovery of Carbono(di)thioates as Indoleamine 2,3-Dioxygenase 1 Inhibitors. ACS Medicinal Chemistry Letters, 2021 in press
https://pubs.acs.org/doi/10.1021/acsmedchemlett.0c00527

10. Ayaka Kon, Shunsuke Omata, Yuhei Hayakawa, Nobuhiro Aburai, Katsuhiko Fujii. Microflora communities which can convert digested sludge to biogas. Environmental Technology, 2021 in press
https://www.tandfonline.com/doi/abs/10.1080/09593330.2021.1880489